杂交品种的遗传和基因组模型中的品种和当地品种比例之间的分离
Jón H Eiríksson1,2, Guosheng Su3, Ismo Strandén4
1Center for Quantitative Genetics and Genomics, Aarhus University, 8000, Aarhus C, Denmark. jonhjalti@lbhi.is.
Genetics, selection, evolution : GSE
|July 5, 2023
概括
杂交动物的品种隔离效应是由当地品种比例 (LBP) 解释的. 纳入LBP效应的基因组模型需要仔细构建 (共差) 结构,以确保准确估计繁殖值.
科学领域:
- 动物育种与遗传学
- 量化遗传学 量化遗传学
- 基因组预测 基因组预测
背景情况:
- 理论上,杂交品种的繁殖价值可以解释品种贡献和品种隔离.
- 品种隔离是由于品种之间的等位基频率差异引起的.
- 基因组模型使用基因基因的品种起源 (BOA) 需要方法来纳入品种隔离,特别是在多个交叉繁殖世代.
研究的目的:
- 探索当地品种比例 (LBP) 的理论基础及其与品种隔离的关系.
- 研究将品种隔离 (共变异) 纳入基因组BOA模型的方法.
主要方法:
- 开发了一个理论框架,将LBP效应与品种隔离联系起来.
- 在基因组BOA模型中研究了品种隔离效应的 (共) 差异结构.
- 使用参考品种方法来构建LBP效应的有效 (共同) 差异结构.
主要成果:
- 地方品种比例 (LBP) 效应被证明是由于品种之间的平均位置贡献的差异 (品种隔离效应) 而产生的.
- 在基因组BOA模型中,用于品种隔离效应的标准 (co) 差异结构可能不会产生正的半确定的关系矩阵.
- 通过使用参考品种,并包括其他品种的相关LBP效应,构建了一个有效的 (co) 差异结构.
- 在一个仿真数据集中,成功估计了基因组BOA模型与LBP效应的变异组件.
结论:
- 品种隔离效应和LBP效应提供了替代方法来模拟品种间的位置贡献差异.
- 包括跨品种的LBP效应之间的共变性,以一种品种作为参考,允许有效的 (共变性) 结构构建.
- 这种方法使得每个非参考品种可以适应LBP效应.
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