烟草吸烟和饮酒与动脉硬度之间的关联
1Department of Epidemiology-Data-Biostatistics, Delegation of Clinical Research and Innovation (DRCI), Foch Hospital, Suresnes, France.
Journal of clinical hypertension (Greenwich, Conn.)
|July 6, 2023
概括
这项研究发现,吸烟和饮酒都会增加动脉硬度,特别是在女性中. 戒掉这些习惯对于预防心血管疾病至关重要.
科学领域:
- 心血管健康 心血管健康
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 动脉硬是心血管疾病的重要危险因素.
- 烟草吸烟和饮酒对动脉硬的联合影响的研究有限.
研究的目的:
- 在中年人群中,研究吸烟和饮酒与动脉硬度指数 (ASI) 的关联.
- 探索这些关联和潜在相互作用的性别特异性.
主要方法:
- 利用了来自98,039名英国生物库参与者的数据 (45,457名男性,52,582名女性).
- 采用多重线性回归模型来估计吸烟 (包年,香烟/天) 和酒精 (单位/天) 与ASI之间的关联.
- 研究了吸烟和饮酒之间的相互作用和协同效应.
主要成果:
- 与女性相比,男性的ASI水平较高.
- 目前的吸烟者在两性中比从未吸烟者有显著更高的ASI.
- 在两性中,酒精消费与较高的ASI积极相关,尽管这种关系比吸烟更弱.
- 在男性中发现吸烟和饮酒之间的相互作用,在吸烟和饮酒相结合时,在两性中观察到协同效应.
结论:
- 吸烟和饮酒都独立地与动脉硬度增加有关.
- 吸烟和动脉硬之间的关系在女性中更为强烈.
- 建议在心血管疾病预防策略中结合戒烟和戒酒.
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