伴随性疾病与日本大脑麻的成年人2年死亡率相关
Yoh Fujimoto1,2, Eiji Nakatani1, Yasuharu Tabara1,3
1Graduate School of Public Health, Shizuoka Graduate University of Public Health, Shizuoka, Japan.
Developmental medicine and child neurology
|July 6, 2023
概括
惠特尼并发症指数 (WCI) 对于脑 (CP) 的成年人来说是有效的,并且在包括吸气性肺炎和压力时改善死亡率预测. 这个工具有助于识别风险CP患者.
科学领域:
- 医学研究 医学研究
- 公共卫生 公共卫生
- 临床流行病学临床流行病学
背景情况:
- 大脑 (CP) 影响成年人,需要准确的预后工具.
- 惠特尼并发症指数 (WCI) 是评估CP群体并发症负担的潜在措施.
- 之前的研究还没有完全验证WCI在不同种族群体,特别是亚洲成年人CP.
研究的目的:
- 评估惠特尼并发症指数 (WCI) 在患有脑 (CP) 的亚洲成年人中的有用性.
- 为了确定吸入性肺炎和压力是否会增加WCI的预后意义.
- 将WCI的预测性能与其他并发症指数进行比较.
主要方法:
- 一项在日本参与CP的2232名成年人 (≥18岁) 的队列研究.
- 考克斯比例危险回归分析用于评估2年死亡率.
- 查尔森并发症指数,埃利克沙瑟并发症指数和WCI的预测准确性被比较,并将吸入性肺炎和压力添加到模型中.
主要成果:
- 该模型包含一个加权的WCI与吸入性肺炎和压力的模型证明最适合预测死亡率.
- 未加权的WCI得分≥4与2年死亡率的2.56危险比率有关.
- 添加CP特异性并发症,包括吸入性肺炎和压力,使危险风险增加到8.94.
结论:
- 惠特尼并发症指数 (WCI) 是评估亚洲成人CP并发症的有效工具.
- 结合患者年龄,吸气性肺炎和压力,显著提高了WCI对死亡率的预测值.
- 加上特定的并发症,WCI有效地识别了患有CP的成年人具有更高的不良结果风险,并促进了国际比较.
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