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Updated: Jul 24, 2025

Visualization of Vascular Ca2+ Signaling Triggered by Paracrine Derived ROS
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罗亚-ROCK1/ROCK2通路在不朽化和初级微质中加剧炎症信号

Elliot J Glotfelty1,2, Luis B Tovar-Y-Romo3, Shih-Chang Hsueh1

  • 1Drug Design & Development Section, Translational Gerontology Branch, Intramural Research Program National Institute on Aging, NIH, Baltimore, MD 21224, USA.

Cells
|July 6, 2023
PubMed
概括

神经炎症涉及RhoA/ROCK信号传递,抑制剂可减少微质细胞中的促炎因素. 这一途径与阿尔茨海默病有关,这表明了潜在的治疗点.

关键词:
在 NF-κBB 中.对于 ROCK 抑制剂来说,它们是非常有效的.在Rock1上,你会看到Rock1.在Rock2上,我一直在努力.在RhoAAA微质细胞中的微质细胞神经炎症是一种神经炎症.

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