耳聋会导致背部听力皮层的腰带区域的完全交叉可塑性
Yaser Merrikhi1, Ali Mirzaei2, Melanie A Kok3
1Department of Physiology, Faculty of Medicine, McGill University, Montreal, Quebec, Canada.
The European journal of neuroscience
|July 6, 2023
概括
聋猫在听觉皮层中表现出显著的交叉可塑性,神经元对视觉和体感官输入作出反应. 这种生理学重组支持听力损失后增强的感官处理.
科学领域:
- 神经科学是一个神经科学.
- 听觉神经科学 听觉神经科学
- 感官可塑性 感官可塑性
背景情况:
- 在失聪后,神经活动的模式往往会消失.
- 其余的感觉系统可以激活这些神经区域,这种现象被称为交叉模式可塑性.
- 跨模式可塑性在感知/行为和生理层面都可以观察到.
研究的目的:
- 调查早期聋猫在听力皮层的背部区域 (DZ) 的交叉模式重组的生理水平.
- 为了检查在聋和听猫的DZ中对视觉,听觉,体感和联合刺激的神经元反应.
主要方法:
- 使用多种单通道记录方法.
- 研究了早期聋猫和听力控制器.
- 检查了神经元对各种感官刺激的反应.
主要成果:
- 在早期聋猫的DZ中没有观察到听觉激活.
- 聋人DZ中100%的神经元对视觉线索做出了反应.
- 聋人DZ中21%的神经元也受到体感刺激的影响.
- 聋猫的视觉和体感反应缺乏听力猫的解剖组织.
- 与听力控制对象相比,在聋人中存在的多感官神经元较少.
结论:
- 聋猫的听觉皮层中的生理交叉模式重组是相当大的.
- 在聋猫的听觉皮层中观察到的生理变化与已知的感知/行为增强相对应并支持.
- 这些发现凸显了大脑在应对感官损失时适应和重组的非凡能力.
更多相关视频
11:39Assessment of Audio-Tactile Sensory Substitution Training in Participants with Profound Deafness Using the Event-Related Potential Technique
Published on: September 7, 2022
2.2K
10:05A Large Lateral Craniotomy Procedure for Mesoscale Wide-field Optical Imaging of Brain Activity
Published on: May 7, 2017
12.3K
相关概念视频
Neuroplasticity
588
Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
588
Auditory Pathway
5.5K
Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
5.5K
Auditory Perception
385
The auditory system is essential for sound perception, utilizing various critical structures. When sound waves enter the outer ear, they travel through the ear canal and cause the eardrum to vibrate. These vibrations are then transmitted to the middle ear, where three tiny bones – the malleus, incus, and stapes – amplify the sound. This amplification is crucial, as it ensures that the sound vibrations are strong enough to be conveyed to the inner ear. These vibrations then reach the...
385
The Cochlea
45.2K
The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
45.2K
Hearing
52.5K
When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
52.5K
Perceiving Loudness, Pitch, and Location
241
The human brain perceives pitch through two primary mechanisms reflected in place theory and frequency theory. Each mechanism describes how sound waves are interpreted as specific pitches by the brain, offering insights into the intricate processes of auditory perception.
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by...
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by...
241
