儿童注意力缺陷多动症问题和中年心血管风险:前性人口队列研究
Ajay K Thapar1, Lucy Riglin1, Rachel Blakey2
1Division of Psychological Medicine and Clinical Neurosciences, Centre for Neuropsychiatric Genetics and Genomics, Wolfson Centre for Young People's Mental Health, Cardiff University School of Medicine, Cardiff, UK.
概括
儿童注意力缺陷多动症 (ADHD) 与成人心血管风险因素的增加有关. 早期发现ADHD可能使得及时进行干预以减轻这些风险.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 发展心理学 发展心理学
背景情况:
- 众所周知,儿童注意力缺陷多动症 (ADHD) 与不良的心理健康和社会结果相关.
- 研究表明,ADHD和晚期心血管疾病 (CVD) 之间存在潜在联系,但预防策略尚不清楚.
- 很少有队列研究研究了儿童ADHD与成年人心血管风险因素之间的关联.
研究的目的:
- 调查儿童ADHD与成年期中期客观测量的心血管风险因素之间的关联.
- 利用英国国家儿童发育研究 (NCDS) 的数据进行基于人口的队列分析.
主要方法:
- 儿童多动症在7岁时使用家长和教师的评分来确定.
- 心血管风险因素,包括血压,BMI,脂质概况和吸烟状况,在44/45岁时被评估.
- 这项研究分析了8016名儿童和中年评估的个人数据.
主要成果:
- 大约3.0%的参与者表现出童年多动症问题.
- 儿童多动症与显著更高的体重指数,缩和腹缩血压以及三糖水平有关.
- 患有童年多动症的个体也更有可能是目前的吸烟者,尽管没有发现与LDL胆固醇的关联.
结论:
- 童年ADHD问题预测到中年时,多种心血管风险因素.
- 这些发现支持对患有多动症的人进行心血管风险监测的必要性.
- 对ADHD的早期识别和干预可能有助于管理可修改的心血管风险因素.
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