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创伤性粘膜菌,由阿波菲索米塞斯物种引起 - 一个案例系列
Vithiya G1, Rajendran T1, Ramesh A1
1Department of Microbiology, Velammal Medical College Hospital and Research Institute, Madurai, India.
Journal of orthopaedics
|July 6, 2023
概括
在印度,Apophysomyces物种会导致粘膜菌,通常会影响免疫能力强的个体,患有死性膜炎. 创伤病例的早期怀疑对于及时诊断和治疗这种新出现的真菌感染至关重要.
科学领域:
- 医学真菌学 医学真菌学
- 传染性疾病 传染性疾病
背景情况:
- 在印度,Apophysomyces物种是粘膜菌的第二大常见原因.
- 这种真菌感染主要影响免疫能力强的宿主,与其他真菌菌不同.
- 一种常见的表现是死性筋膜炎,这可能被误诊为细菌感染.
研究的目的:
- 提高骨科外科医生对阿波菲索米塞斯相关的粘膜菌的认识.
- 强调在创伤后软组织感染的患者中考虑创伤性粘膜菌病的重要性.
主要方法:
- 在2019年1月至2022年9月期间,对7例阿波菲索米切斯粘膜菌病例进行了回顾性分析.
- 型识别的真菌分离物作为Apophysomyces变异性.
- 对临床表现,治疗和结果的审查.
主要成果:
- 诊断了7名男性患者,平均年龄为55岁.
- 六名患者出现了死软组织感染,通常是创伤后的,其中四人患有多重骨折.
- 诊断的中位时间为9天;患者接受了手术脱bridement和/或截肢,死亡率为43%.
结论:
- Apophysomyces 粘膜菌是一种新兴的威胁,特别是在创伤后免疫能力强的个体中.
- 早期怀疑和诊断至关重要,特别是在土壤污染导致软组织死感染的情况下.
- 骨科专家之间提高意识是必要的,以便及时管理.
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