完全厚度黄斑孔开始与后部玻璃体脱离之间的关系:一个时间开始理论
Hirokazu Sakaguchi1,2, Daijiro Kabata3, Susumu Sakimoto1
1Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan.
Ophthalmology science
|July 6, 2023
概括
全厚斑点孔的出现与后部玻璃体脱落有关. 较大的分离高度增加了内裂的风险,通常是暂时出现的.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜科学 视网膜科学
- 医疗成像医学成像
背景情况:
- 全厚黄斑孔 (FTMH) 是视力障碍的一个重要原因.
- 了解FTMH发展的早期阶段对于及时干预至关重要.
- 后面玻璃体脱落 (PVD) 在斑点孔的病变发生中起着关键作用.
研究的目的:
- 为了研究围膜后部玻璃体脱落与全厚黄斑孔的出现之间的关联.
- 分析后部玻璃体分离高度 (PVSH) 和黄斑孔 (MH) 阶段化之间的关系.
- 确定PVSH的预测值及其在内裂形成中的定向性.
主要方法:
- 从742名患有FTMH或即将出现MH的患者的光学连贯性断层扫描 (OCT) 数据的回顾性分析.
- 在四个主要方向 (鼻腔,腔,上腔,下腔) 计算PVSH,距离腔1毫米.
- PVSH与MH阶段的相关性,玻璃瘤粘附 (VMA),以及叶内部撕裂的存在和位置.
主要成果:
- 随着MH阶段的增加,PVSH表现出增加的趋势:VMA
- 较高的PVSH显着与叶内部撕裂的可能性增加有关 (P=0.002).
- 与鼻腔方向相比,面方向更有可能呈现出面内部撕裂 (P=0.002).
结论:
- FTMH的发病与周围膜后部玻璃体脱落的程度有很强的相关性.
- 体内部撕裂的可能性随着后部玻璃体分离高度的增加而增加.
- 在FTMH发作时,状内部撕裂在侧或PVSH较高的侧面更有可能发生.
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