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辅助复合冷大气等离子体疗法增加了多克索鲁比辛化的抗瘤作用

Volha Kniazeva¹, Dzmitry Tzerkovsky², Ömür Baysal³

¹Bioresearch Department, R. S. C. Real Scientists Cyprus Ltd., Limassol, Cyprus.

Frontiers in oncology

|July 6, 2023

概括

这项研究表明,将冷大气等离子体与化疗相结合,可显著抑制大鼠的淋巴肉瘤瘤生长. 这种新的方法,使用冷血和离子疗法,为癌症治疗提供了一个有前途的新途径.

科学领域:

在瘤学瘤学.
生物物理学的生物物理.
生物医学工程生物医学工程

背景情况:

癌症治疗面临着高成本和瘤耐药性等挑战,需要新的治疗策略.
冷大气等离子体 (CAP) 具有临床前的抗性作用,但其与淋巴肉瘤离子结合的使用尚未被探索.
向性抗瘤药物具有局限性,推动了对替代性和补充性疗法的研究.

研究的目的:

为了评估复合冷血和控制的离子疗法在淋巴肉瘤大鼠模型中的抗瘤疗效.
为了研究结合冷血治疗与化疗 (多克索鲁比辛化物) 的协同效应.
评估PERENIO IONIC SHIELDTM与冷血对瘤生长的影响.

主要方法:

一个体内研究使用了普利斯淋巴肉瘤大鼠模型.
鼠被暴露在复合冷血中3,7天和14天,对照组没有接受任何治疗.
组合治疗包括多克索鲁比辛化物 (5毫克/公斤) 和PERENIO IONIC SHIELDTM离子疗法.

主要成果:

与对照组相比,复合冷血暴露导致显著的瘤生长抑制.
结合化疗和冷血治疗,导致瘤体积减少了三倍.
用多克索鲁比辛化和14天的PERENIO IONIC SHIELDTM离子疗法获得了最佳的抗瘤效果.

结论:

复合冷血和控制的离子疗法显示出作为淋巴肉瘤辅助治疗的前景.
组合疗法,特别是多克索鲁比辛化,增强了抗瘤功效.
需要进一步的研究来阐明机制,并评估在人体试验中的临床适用性.

关键词:

寒冷大气等离子体 (CAP) 的使用.复合离子是复合离子.离子发射器离子发射器淋巴细胞癌 (Lymphosarcoma) 是一种癌症.血疗法是一种血疗法.

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