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Updated: Jul 24, 2025

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考古Hel308通过控制DNA回火的催化开关抑制了重组

Rebecca J Lever1, Emily Simmons1, Rebecca Gamble-Milner1

  • 1School of Life Sciences, University of Nottingham, Nottingham NG7 2UH, UK.

Nucleic acids research
|July 6, 2023
PubMed
概括

古代生物的Hel308蛋白对基因组稳定至关重要,它使用IVa图案来控制DNA修复和重组. 这种基因的突变会增加它的活性,导致基因转换增加,但不会影响细胞活力.

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