鼻包装材料和放置时间对鼻粘液中伤口愈合的影响:一项动物研究
Kosuke Tochigi1, Teru Ebihara2, Kazuhiro Omura1,2
1Department of Otorhinolaryngology/Head and Neck Surgery, Dokkyo Medical University Saitama Medical Center, Saitama, Japan.
The Laryngoscope
|July 6, 2023
概括
像Spongel®,Algoderm®和Nasopore®这样的鼻包装材料显著影响鼻腔伤口愈合. 较短的更换时间 (3-7天) 比较长的时间 (14天) 促进更好的愈合,特别是当材料被完全吸收时.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 生物材料科学 生物材料科学
- 伤口治愈研究研究 伤口治愈研究
背景情况:
- 关于鼻子伤口愈合受包装材料和持续时间影响的组织学数据有限.
- 鼻包装对于术后护理和组织再生至关重要.
研究的目的:
- 评估不同鼻腔包装材料 (Spongel®,Algoderm®,Nasopore®) 对鼻隔膜伤口愈合的组织学影响.
- 为了确定不同更换时间对愈合过程的影响.
主要方法:
- 子鼻隔膜粘膜缺陷被制造并用Spongel®,Algoderm®或Nasopore®进行治疗.
- 在3,7或14天后取出Spongel®;在14天后取出其他材料.
- 组织学分析评估了表皮质等级得分和28天后的亚皮质厚度,比较了残留和非残留组.
主要成果:
- 14天后的Spongel®和14天后的Algoderm®与其他组相比显示出较低的上皮质得分和较高的亚上皮质厚度.
- 较短的Spongel®持续时间 (3天和7天) 导致更好的上皮质得分和更低的亚上皮质厚度.
- 剩余的包装材料 (残留组) 对愈合产生了负面影响,表现出较低的上皮质得分和较高的亚上皮质厚度.
结论:
- 鼻包装材料的类型和持续时间显著影响鼻膜的伤口愈合.
- 选择合适的包装材料和更换时间对于最佳的鼻腔伤口愈合至关重要.
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