相关实验视频

Updated: Jul 24, 2025

Analysis of β-Amyloid-induced Abnormalities on Fibrin Clot Structure by Spectroscopy and Scanning Electron Microscopy
06:27

Analysis of β-Amyloid-induced Abnormalities on Fibrin Clot Structure by Spectroscopy and Scanning Electron Microscopy

Published on: November 30, 2018

9.3K

通过REMD模拟进行的跨膜Aβ42四聚体的形态学

Son Tung Ngo1,2, Trung Hai Nguyen1,2, Van V Vu3

  • 1Laboratory of Biophysics, Institute for Advanced Study in Technology, Ton Duc Thang University, Ho Chi Minh City 72915, Vietnam.

Journal of chemical information and modeling
|July 6, 2023
PubMed
概括

阿尔茨海默氏病涉及到胺β (Aβ) 的错误折叠. 模拟显示Aβ在膜内形成多样化的孔状结构,可能会影响平衡.

更多相关视频

Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy12:58

Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy

Published on: September 12, 2019

9.8K
Modeling Amyloid-β42 Toxicity and Neurodegeneration in Adult Zebrafish Brain10:01

Modeling Amyloid-β42 Toxicity and Neurodegeneration in Adult Zebrafish Brain

Published on: October 25, 2017

11.3K

相关概念视频

Amyloid Fibrils03:03

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining,...
9.6K