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Updated: Jul 24, 2025

Assessment of Resistance to Tyrosine Kinase Inhibitors by an Interrogation of Signal Transduction Pathways by Antibody Arrays
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Assessment of Resistance to Tyrosine Kinase Inhibitors by an Interrogation of Signal Transduction Pathways by Antibody Arrays

Published on: September 19, 2018

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针对铁蛋白激酶JAK-2抑制剂的现场3D-QSAR

Sowmya Andole1, Gouthami Thumma2, Rajasekhar Reddy Alavala3

  • 1School of Pharamcy, Anurag University, Venkatapur, Ghatkesar, Medchal-Malkajgiri district, Hyderabad, Telangana, India.

Journal of biomolecular structure & dynamics
|July 6, 2023
PubMed
概括

这项研究开发了一种3D-QSAR模型,用于识别用于治疗自身免疫和骨髓增殖性疾病的新的Janus Kinase 2 (JAK-2) 抑制剂. 该模型成功预测了抑制活性,并指导虚拟查,识别了有前途的候选药物.

关键词:
3D-QSAR 是一个3D-QSAR.雅克-抑制剂的使用基于现场的QSAR.药物学家模型的模型.虚拟选 虚拟选 虚拟选

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