在一个大型多级多组分干预试验中,农村美洲原住民成年人的心脏代谢风险
Leslie C Redmond1, Michelle Estradé2, Margarita S Treuth3
1Dietetics & Nutrition Department, University of Alaska Anchorage, Anchorage, AK, United States of America.
PLOS global public health
|July 6, 2023
概括
农村地区的美国原住民成年人显示肥胖和心血管风险因素的高率,但很少有人报告正式诊断. 这凸显了慢性疾病的识别和管理方面的潜在差距.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 美国原住民健康 美国原住民健康
背景情况:
- 肥胖,高血压和糖尿病等慢性疾病不成比例地影响着美洲原住民人口.
- 了解农村美洲原住民社区中这些疾病的患病率和相关风险因素对于有针对性的干预至关重要.
研究的目的:
- 评估美国中西部和西南部农村社区的美洲原住民成年人中肥胖,高危人体构成和高血压的患病率.
- 检查自我报告的慢性病家族病史和测量健康指标之间的关系.
主要方法:
- 从美国原住民肥胖预防和评估干预有效性的研究2 (OPREVENT2) 的基线数据的横截面分析.
- 包括601名来自农村保留社区的美国原住民成年人 (18至75岁).
- 数据收集包括自我报告问卷和身体质量指数 (BMI),腰比,百分比体脂肪和血压的客观测量.
主要成果:
- 大约60%的参与者BMI超过30kg/m2,表明肥胖.
- 大约80%的人表现出高风险的腰部和部比率和百分比的身体脂肪.
- 近64%的患者进行了高风险血压测量.
- 很大一部分人报告家族有慢性病史,但很少有人自我报告诊断.
结论:
- 该研究中的农村美洲原住民成年人表现出肥胖和心血管疾病风险因素的高负担.
- 在客观测量的健康风险和自我报告的疾病诊断之间存在显著的不一致.
- 需要进一步的研究来探索医疗保健获取在这种差异中的作用,并改善这些社区的慢性疾病管理.
相关概念视频
Coronary Artery Disease IV: Preventive Measures
25
Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
25
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
123
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
123
Blood Studies for Cardiovascular System I: Cardiac Biomarkers
203
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
203
Hypertension IV: Drug Therapy and Lifestyle Modifications
17
Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...
17
Coronary Artery Disease I: Introduction
25
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
25
Lifestyle Factors and Health
88
Lifestyle factors play a critical role in maintaining overall health and preventing chronic diseases. Key elements, such as regular physical activity, a nutritious diet, and abstinence from smoking, can significantly enhance physical, mental, and emotional well-being while reducing the risk of several life-threatening conditions.
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
88


