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Updated: Jul 24, 2025

Forskolin-induced Swelling in Intestinal Organoids: An In Vitro Assay for Assessing Drug Response in Cystic Fibrosis Patients
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在COPD中使用CFTR增强剂Icenticaftor:一个多中心,并行组,双盲临床试验

Fernando J Martinez1, Gerard J Criner2, Christian Gessner3

  • 1Division of Pulmonary and Critical Care Medicine, Weill Cornell Medicine/NewYork-Presbyterian Hospital, New York, New York.

American journal of respiratory and critical care medicine
|July 6, 2023
PubMed
概括

在COPD患者中,Icenticaftor在12周后没有改善肺功能 (FEV1). 然而,在24周,这种CFTR增强剂在减少咳,和救援药物的使用方面表现出好处,300mg剂量是最有效的.

关键词:
在CFTR功能障碍.在CFTR增强器中,慢性慢性肺炎是一种慢性慢性肺炎,COPD是一种慢性肺炎.慢性支气管炎是一种慢性支气管炎.这是一个令人难以置信的机器人.

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