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Updated: Jul 24, 2025

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CD4+调节性T细胞缺少Helios和Eos的细胞

Katarzyna Polak1, Patricia Marchal1, Chiara Taroni1

  • 1Université de Strasbourg, IGBMC UMR 7104- UMR-S 1258, F-67400 Illkirch, France; CNRS, UMR 7104, F-67400 Illkirch, France; Inserm, UMR-S 1258, F-67400 Illkirch, France; IGBMC, Institut de Génétique et de Biologie Moléculaire et Cellulaire, F-67400 Illkirch, France.

Biochemical and biophysical research communications
|July 6, 2023
PubMed
概括

(Ikzf2) 和Eos (Ikzf4) 是对调节T (Treg) 细胞功能至关重要的转录因子. 虽然两者都是最佳的Foxp3表达所需的,但它们调节不同的基因,并在Treg细胞衰老和整体功能中发挥非冗余的作用.

关键词:
衰老的衰老 衰老的衰老功能特异性的功能特异性.赫利奥斯和埃奥斯的转录因子淘汰出局的老鼠模型监管性T细胞 监管性T细胞

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