重症手术患者妄的长期结果:一个多中心前性队列研究
Puriwat To-Adithep1, Kaweesak Chittawatanarat2, Sirirat Mueankwan3
1Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Journal of psychosomatic research
|July 6, 2023
概括
手术后痴呆症显著增加了手术重症监护室患者的死亡率和依赖率. 识别年龄和手术前痴呆症等风险因素对于更好的结果至关重要.
科学领域:
- 关键护理医学 关键护理医学
- 外科手术的结果
- 神经科学是一个神经科学.
背景情况:
- 手术后妄 (POD) 是重症手术患者的常见并发症.
- 了解POD的长期后果,包括死亡率和功能依赖,对于改善患者护理至关重要.
研究的目的:
- 确定入住外科重症监护室 (SICU) 的患者的12个月死亡率和依赖率.
- 确定与SICU入院后12个月死亡率和依赖性相关的独立风险因素,重点关注POD.
主要方法:
- 一项前性多中心研究,涉及入住SICU的重症手术患者.
- 在ICU入院后12个月进行了随访,以评估死亡率和功能结果 (日常生活的基本活动).
主要成果:
- 术后妄 (POD) 在27%的患者中存在,与12个月死亡率 (44.1%与18.3%) 显著增加有关.
- 死亡的独立风险因素包括年龄,糖尿病,手术前痴呆症,高SOFA分数和POD.
- 12个月的依赖率为52%,POD是一个独立的风险因素 (调整后的风险比,1.26).
结论:
- 手术后妄是重症手术患者12个月死亡的独立风险因素.
- POD也与SICU入院12个月后的更高依赖率有显著的关联.
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