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Updated: Jul 24, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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含有N-异环碳素醇药物的银(I) 复合物:合成,表征,细胞毒性活性及其BSA相互作用

Camila Aparecida da Silva Dos Reis Condé1, Ana Luiza de Andrade Querino2, Heveline Silva2

  • 1Laboratório de Química Bioinorgânica e Catálises (LaQBIC), Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Juiz de Fora, Juiz de Fora, MG, Brazil.

Journal of inorganic biochemistry
|July 6, 2023
PubMed
概括

抗真菌药物克洛特里马和凯托可纳被重新定位为抗癌药物. 从这些药物中提取的银 (I) 复合物显示出显著的抗癌活性,具有蛋白介导药物递送的潜力.

关键词:
专辑中的专辑蛋白.抗癌药物 抗癌药物 抗癌药物克洛特里马 (Clotrimazole) 是一种药物.凯托可纳醇 (Ketoconazole) 是一种可靠的药物.在 NHC 连接物中,连接物是 NHC 连接物.银(I) -NHC复合体的复合物

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