正常化可以提高腹部MRI放射性特征的稳定性吗?
Valentina Giannini1,2, Jovana Panic2,3, Daniele Regge2
1University of Turin, Department of Surgical Science, Turin, Italy.
Biomedical physics & engineering express
|July 6, 2023
概括
功能规范化方法显著提高了不同扫描仪和机构的放射学功能稳定性,与图像规范化技术不同. 对于可复制癌症成像分析,ComBat,z-score和3-sigma规范化是最有效的.
科学领域:
- 医疗成像医学成像
- 无线电学 (Radiomics) 是一种无线电学.
- 在瘤学瘤学.
背景情况:
- 放射学增强了癌症患者的管理,但普遍性受到多中心,多扫描仪数据的限制.
- 图像和特征正常化是为了解决放射学中的可重现性问题而提出的.
研究的目的:
- 为了评估各种图像和特征规范化方法对放射学特征强度的影响.
- 用多中心,多扫描器腹部MRI数据集来评估正常化技术的性能.
主要方法:
- 追溯收集88个直肠MRI来自3个机构 (4个扫描仪).
- 分析了来自6个3D感兴趣区域的93个放射特征,这些特征来自闭塞肌的3D感兴趣区域.
- 应用和比较min-max,1st-99th百分位数,3-Sigma,z-score,平均中心化,直方图规范化,Nyul-Udupa和ComBat协调.
主要成果:
- 图像正常化方法通常会降低强度变化,但往往会降低特征强度.
- 从9/93年到10/93年,Z-score图像规范化略有改善了特征相似性.
- 特征规范化方法,特别是3-sigma,z-score和ComBat,大大提高了与79/93的特征相似性.
- 没有图像规范化方法强烈增加了统计上相似的特征的数量.
结论:
- 特征正常化,特别是ComBat,z-score和3-sigma,对于提高多中心研究中的放射学特征稳定性至关重要.
- 仅仅是图像规范化不足以保证在不同成像环境中放射学发现的概括性.
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