在前膜炎中白内障的发生率和风险因素
George N Papaliodis1, Bernard A Rosner2, Kurt A Dreger3
1From the Department of Ophthalmology, Massachusetts Eye and Ear Infirmary (G.N.P., J.H.K.), Boston, Massachusetts, USA; Department of Ophthalmology, Harvard Medical School (G.N.P., C.S.F., J.H.K.), Boston, Massachusetts, USA.
American journal of ophthalmology
|July 6, 2023
概括
每年大约5.4%的非传染性前膜炎眼睛出现白内障. 风险因素包括年龄较大,炎症严重程度,青光眼手术和特定的眼睛疾病,指导风险管理策略.
科学领域:
- 眼科医生 眼科 眼科
- 炎症性眼部疾病 炎症性眼病
- 白内障的研究研究.
背景情况:
- 前膜炎是视力障碍的一个重要原因.
- 白内障形成是慢性眼睛炎症的常见并发症.
- 了解风险因素对于患者管理和预防视力丧失至关重要.
研究的目的:
- 为了确定患有非传染性前膜炎的患者白内障的发病率.
- 在这个患者群体中确定与白内障发展相关的风险因素.
主要方法:
- 在6个美国三级脑膜炎部位进行了一项回顾性多中心队列研究.
- 分析了从1978年至2010年期间被诊断患有前膜炎的2567名患者的3923只眼睛的数据.
- 白内障发病率是由视力敏度降低或白内障手术定义的;风险因素是使用时间更新的考克斯回归来评估的.
主要成果:
- 白内障的发病率约为每100个眼年中5.4个.
- 显著的危险因素包括年龄较大 (≥65岁),较高的前腔细胞等级,先前的切割性玻璃眼瘤手术,带状角膜病变,后部,以及眼内压力升高.
- 与急性形式相比,慢性前膜炎的风险更高. 局部皮质类固醇的使用与白内障风险增加有关,只有当前腔细胞最小或不存在时.
结论:
- 白内障是非传染性前膜炎的常见并发症,具有显著的发病率.
- 已经确定了几种可修改和不可修改的风险因素,允许使用风险分层系统.
- 这些发现表明,与局部皮质类固醇相关的白内障风险取决于情境,特别是关于活跃炎症的存在.
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