产前心肌病症:一篇综述
Rajni Bala1, Sakshi Mehta2, Vikas C Roy3
1Department of Biotechnology, Punjabi University, Patiala, India; Adduct Healthcare Pvt. Ltd., Mohali, India.
概括
产前心肌病是一种罕见的心力衰竭,影响孕妇或产后妇女. 虽然风险包括年龄和多亲症,但超过一半的患者在一年内恢复左心室功能.
科学领域:
- 心脏病学 心脏病学
- 产科 产科 产科 产科 产科
- 遗传学 是一个遗传学.
背景情况:
- 产周心肌病 (PPCM) 是一种罕见的心力衰竭,在怀孕晚期或产后发展.
- 全球范围内的发病率因定义,人口统计和报告不足而有所不同.
- 风险因素包括种族,族裔,多夫妻制和晚年孕产妇年龄.
研究的目的:
- 审查对周边心肌病的理解.
- 概述诊断和管理策略.
- 讨论预后和复发风险.
主要方法:
- 关于周周心肌病的文献综述.
- 分析诊断工具,包括心电图,心声学,核磁共振,活检和生物标志物.
- 审查治疗选择,从标准的心力衰竭药疗到新型药物和机械支持.
主要成果:
- PPCM呈现为心力衰竭,左心室排气分数减少 (<45%),通常与腔室扩张和功能受损.
- 病原发生是多因素的,涉及血液动力学,荷尔蒙,炎症,免疫学和遗传因素.
- 死亡率高达10%,在随后的怀孕中复发的风险很高,但超过50%的人在一年内实现了LV功能恢复.
结论:
- 早期诊断和治疗对于周周心肌病至关重要.
- 标准的心力衰竭治疗适用于怀孕和哺乳期的安全性.
- 在严重的病例中,可能需要针对性治疗和先进的干预措施,并且正在研究像烯胺这样的新疗法.
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