2023年COVID-19疫苗反应的最新情况:进展和理解
Kimberly G Blumenthal1, Matthew Greenhawt2, Elizabeth J Phillips3
1Division of Rheumatology, Allergy and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, Mass; The Mongan Institute, Massachusetts General Hospital, Boston, Mass; Harvard Medical School, Boston, Mass.
概括
尽管接种了数十亿剂量,但COVID-19疫苗的严重不良反应很少见. 大多数反应都是轻微的,暂时的,不会阻止未来的疫苗接种.
科学领域:
- 免疫学 免疫学 免疫学
- 疫苗学 疫苗学 疫苗学
- 公共卫生 公共卫生
背景情况:
- 随着COVID-19大流行,全球接种了超过132亿剂的疫苗,导致了广泛的疫苗接种.
- 使者RNA疫苗是主要使用的类型,数百万人接受多剂量.
- 虽然轻微的副作用很常见,但COVID-19疫苗接种后的严重反应并不常见.
研究的目的:
- 为 COVID-19 疫苗反应提供最新的视角.
- 审查这些反应的频谱和流行病学.
- 概述评估和管理的推方法.
主要方法:
- 这是一个临床管理审查.
- 该审查综合了有关COVID-19疫苗不良事件的当前数据.
- 它侧重于即时和延迟反应,包括类似过敏反应的反应.
主要成果:
- 在COVID-19疫苗接种后,轻微的局部和全身不良反应是常见的.
- 严重的不良事件是罕见的,相对于大量的剂量管理.
- 大多数反应不会复发,导致持久问题,或违反随后的疫苗接种.
结论:
- 接种COVID-19疫苗的反应通常是轻微的和短暂的.
- 鉴于全球免疫接种的规模,COVID-19疫苗的安全概况仍然有利.
- 临床管理应侧重于准确的评估和保证,并罕见地对再接种疫苗有禁忌.
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