截然不同的前端对称脑动力学是自闭症和多动症多动症的共同发生的基础
Daichi Watanabe1,2, Takamitsu Watanabe3
1College of Letters and Science, University of California, Berkeley, Berkeley, CA 94720.
eNeuro
|July 6, 2023
概括
自闭症谱系障碍 (ASD) 和注意力缺陷/多动症障碍 (ADHD) 可以同时发生. 这项研究表明,患有自闭症和多动症的儿童的多动症状特征源于独特的大脑动态,而不仅仅是症状的重叠.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 精神病学是一个精神病学.
背景情况:
- 诊断标准现在允许自闭症谱系障碍 (ASD) 和注意力缺陷/多动症障碍 (ADHD) 的同时发生.
- 对于ASD+ADHD并发症的神经生物学基础的了解很少.
- 目前尚不清楚ASD+ADHD是否代表一个简单的重叠或一个独特的条件.
研究的目的:
- 研究ASD+ADHD,纯ASD,纯ADHD和典型发育 (TD) 儿童之间的神经生物学差异.
- 为了确定ASD+ADHD中类似ADHD的特征是否与纯ADHD相比具有独特的神经机制.
主要方法:
- 在具有ASD+ADHD,纯ASD,纯ADHD和TD对照的高功能儿童中比较大脑动态.
- 使用年龄,性别和智商匹配进行参与者选择.
- 分析了与大脑活动模式相关的社会沟通和ADHD类特征.
主要成果:
- ASD+ADHD儿童的自闭症特征显示出过度稳定的大脑动态,类似于纯ASD.
- 在ASD+ADHD中,类似ADHD的特征与独特的神经机制有关,这些神经机制涉及非典型的前对对对控制网络活动和频繁的状态转换.
- 纯ADHD症状与过度灵活的全脑动态和特定网络不稳定性 (背部注意力,左侧头皮层) 有关.
结论:
- ASD+ADHD并发症并不是ASD和ADHD的简单重叠.
- 在ASD+ADHD中,类似ADHD的特征可能代表一种独特的神经生物学状况.
- 研究结果表明,需要针对ASD+ADHD进行特定的诊断方法和量身定制的治疗方法.
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