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Updated: Jul 24, 2025

Intracerebroventricular Treatment with Resiniferatoxin and Pain Tests in Mice
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单糖醇脂酶 保护预突触大麻素1受体免受持续性炎症后内大麻素的脱敏化

Courtney A Bouchet1,2, Kylie B McPherson3, Basile Coutens3

  • 1Department of Neurological Surgery, Oregon Health & Science University, Portland, Oregon 97239.

The Journal of neuroscience : the official journal of the Society for Neuroscience
|July 6, 2023
PubMed
概括

持久性炎症对大麻素受体1 (CB1R) 进行脱敏,降低外源性激动剂的疗效. 然而,内分泌大麻素表现出长时间的效果,降解对于调节腹侧周水管灰色中疼痛信号至关重要.

关键词:
在GPCR中,GPCR是指GPCR.脱敏感化 脱敏感化这是一种内分泌大麻素 (endocannabinoid).这是一种炎症炎症炎症炎症.周边水道灰色 周边水道灰色在突触前的突触前.

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