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Updated: Jul 24, 2025

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
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Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

Published on: July 25, 2020

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在瘤基因中共享的热点突变将狗定位为精确治疗的无与伦比的比较模型

Lucas Rodrigues1, Joshua Watson2, Yuan Feng2

  • 1One Health Company, Inc, 530 Lytton Ave, 2nd Floor, Palo Alto, CA, 94301, USA. lucas@fidocure.com.

Scientific reports
|July 6, 2023
PubMed
概括

狗和人类癌症具有相似的遗传突变,包括TP53.3等关键瘤基因. 这项研究强调狗作为人类癌症研究和向治疗开发的有价值的翻译模型.

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