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Updated: Jul 24, 2025

Enrichment of Native Lipoprotein Particles with microRNA and Subsequent Determination of Their Absolute/Relative microRNA Content and Their Cellular Transfer Rate
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对天然有效的脂质纳米颗粒冠状体的多组学分析显示,高密度脂蛋白是其功能所必需的

Kai Liu1, Ralf Nilsson2, Elisa Lázaro-Ibáñez1

  • 1Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, Gothenburg, Sweden.

Nature communications
|July 6, 2023
PubMed
概括

在脂质纳米粒子 (LNP) 生物冠状体中的高密度脂蛋白 (HDL) 预测了体内输送的有效性. 这一发现为通过优化冠状元组成来增强LNP治疗方法提供了一个框架.

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