科尔西-罗森塔尔盒子对室内空气污染物的影响:使用高分辨率质谱仪进行非向分析
Katherine E Manz1, Robin E Dodson2, Yun Liu3
1School of Engineering, Brown University, Providence, RI, 02912, USA. katherine_manz@brown.edu.
概括
科尔西-罗森塔尔 (CR) 盒子有效减少室内空气污染物. 这些DIY空气过器显著减少挥发性和半挥发性有机化合物,改善室内空气质量.
科学领域:
- 环境科学 环境科学
- 分析化学 分析化学
背景情况:
- COVID-19强调了室内空气质量 (IAQ) 的重要性.
- 科尔西-罗森塔尔 (CR) 盒子作为一种潜在的DIY干预措施来缓解空气传播病原体.
- 电路复合盒可以为减少其他室内空气污染物提供辅助效益.
研究的目的:
- 评估CR盒对室内空气质量的影响.
- 识别和量化受CR盒安装影响的挥发性和半挥发性有机污染物 (VOC和SVOC).
- 评估CR盒在减少广泛的室内空气污染物的有效性.
主要方法:
- 一个自然实验是在一个被占用的办公楼里进行的.
- 在17个房间的CR盒运行前和运行期间,收集了室内空气样本.
- 使用气体染色学高分辨率质谱仪 (GC-HRMS) 和液体染色学高分辨率质谱仪 (LC-HRMS) 分析了VOC和SVOC.
- 使用非向和可疑查分析 (NTA/SSA) 来检测和识别污染物.
- 线性混合模型被用来分析污染物水平的变化.
主要成果:
- 安装CR盒导致71个检测到的特征的显著减少 (50-100%).
- 四种化学物质被确定具有高可靠性,45种被假定确定,22种仍未确定.
- 减少的污染物包括消毒剂,香料,杀虫剂,甲酸盐,PAHs和PFAS.
- 广泛的有机污染物被发现通过使用CR盒减少.
结论:
- 科尔西 - 罗森塔尔自制盒在改善室内空气质量方面是有效的.
- CR盒子显著减少了各种各样的挥发性和半挥发性有机污染物.
- 这些发现支持使用CR盒作为一个实际的IAQ改进策略.
相关概念视频
01:15High-Resolution Mass Spectrometry (HRMS)
1.4K
The resolution of a mass spectrometer depends on the efficiency of separating ions with different ion masses. The mass of an atom is approximated to the sum of the masses of protons and neutrons inside, considering the masses of protons and neutrons as equal. However, the masses of the proton (1.6726 × 10−24 g) and neutron (1.6749 × 10−24 g) are not truly equal. There is a minor error in the expression of atomic masses relative to the simplest atom of hydrogen. For...
1.4K
01:20Inductively Coupled Plasma-Mass Spectrometry (ICP-MS): Interferences
525
Inductively coupled plasma–mass spectrometry (ICP–MS) is a highly selective and sensitive technique for accurate elemental analysis. Though the analysis of ICP–MS mass spectra is comparatively straightforward, it is affected by spectroscopic and non-spectroscopic interferences. Spectroscopic interferences arise when the plasma contains ionic species with an m/z value the same as the analyte ion. Spectroscopic interference can be categorized as isobaric, polyatomic ions, and...
525
01:16Mass Spectrometers
5.7K
This lesson details the instrumentation of a mass spectrometer—a physical instrument to perform mass spectrometry on analyte molecules and record the characteristic mass spectra. This is achieved via three chief functions:
5.7K
01:13Mass Analyzers: Overview
740
The mass analyzer is a crucial component of the mass spectrometer. In the ionization chamber, the vaporized sample is bombarded with a high-energy electron beam to generate a radical cation and further fragment into neutral molecules, radicals, and cations. A series of negatively charged accelerator plates accelerate the cations into the mass analyzer. The mass analyzer separates ions according to their mass-to-charge (m/z) ratios and then directs them to the detector. The common types of mass...
740
01:21Mass Spectrometry: Complex Analysis
829
Mass spectrometry is an important technique for the identification of pure compounds. However, it has some limitations for the analysis of complex mixtures, often due to excessive fragmentation making the spectrum too complicated to decipher. Mass spectrometry can be combined with suitable separation methods in sequence, forming hyphenated methods, which are useful in the analysis of complex mixtures.
GC–MS is a powerful hyphenated method commonly used in forensics and environmental...
GC–MS is a powerful hyphenated method commonly used in forensics and environmental...
829
01:19Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview
812
In inductively coupled plasma–mass spectrometry (ICP–MS), an inductively coupled plasma (ICP) torch is used as an atomizer and ionizer. Solid samples are dissolved and volatilized before being introduced into the high-temperature argon plasma, while solution samples are nebulized and passed through the high-temperature argon plasma. Plasma dissociates the analytes and ionizes their component atoms to form a mixture of positive ions and molecular species. The positive ions are then...
812