右心室的心声压力-应变循环衍生的中风工作:根据黄金标准进行验证
Manuel J Richter1, Philipp Douschan1,2, Federico Fortuni3,4
1Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Klinikstrasse 32, 35392, Giessen, Germany.
ESC heart failure
|July 7, 2023
概括
心声图中风工作 (SW) 测量软件与评估右心室 (RV) 功能的侵入性方法有很好的相关性. 这种经过验证的技术有助于评估RV在肺高血压中的性能.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 血液动力学 血液动力学
背景情况:
- 对于右心室 (RV) 来说,用于心电回声测量中风工作 (SW) 的集成软件越来越多地被使用,但缺乏验证.
- 精确评估RV功能至关重要,特别是在肺动脉高血压 (PAH) 和慢性血栓栓塞性肺高血压 (CTEPH) 等疾病中.
研究的目的:
- 为了验证商业上可用的集成软件对RV SW的回声心脏学测量与黄金标准的侵入性RV压力-体积 (PV) 循环的准确性.
- 评估声心谱衍生RV全球工作指数 (RVGWI) 和RV全球浪费工作 (RVGWW) 与侵入性血液动力学参数的相关性.
主要方法:
- 这项研究包括42名患者 (34名患有PAH/CTEPH,8名对照) 接受了VR心声扫描 (使用集成心肌工作 (MW) 软件) 和侵入性PV导管治疗.
- 声心谱SW被评估为RVGWI,侵入性SW从PV循环区域计算.
- RVGWW是由MW模块衍生而来的,并且与侵入性措施相关联.
主要成果:
- 从集成的MW软件中获得的RVGWI在整体队列 (rho = 0.546,P < 0.001) 和PAH/CTEPH亚组 (rho = 0.568,P < 0.001) 中与侵入性光伏循环衍生的RV SW显示出显著的相关性.
- RVGWW与动脉弹性 (Ea),Ees/Ea比率和终端扩张弹性 (Eed) 的侵入性测量结果有显著的相关性.
结论:
- 使用压力应变循环进行SW的综合回声心脏学测量与基于PV循环的RV SW评估有很好的相关性.
- 反响心脏学参数RVGWW与负载独立RV功能的侵入性测量相关.
- 进一步完善这种回声心脏学方法,结合高级分析和RV参考曲线,可以提高其可靠性,以反映侵入性评估的RV SW.
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