慢性心力衰竭患者的铁状况的临床和心声学相关值:一个横截面描述性研究

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Uchenna M Amaechi¹, Ewelukwa Chukwudum², Henry O Aiwuyo³

¹Internal Medicine, Lagos University Teaching Hospital, Lagos, NGA.

Cureus

|July 7, 2023

概括

慢性心力衰竭 (HF) 患者常见的缺铁 (ID) 与更严重的疾病有关. 早期对ID的评估可以改善HF管理和患者的治疗结果.

科学领域:

心脏病学心脏病学
营养科学营养科学

背景情况:

慢性心力衰竭 (HF) 是一个普遍的疾病.
铁缺乏症 (ID) 是HF患者最常见的营养缺乏症.
ID可能会对HF临床参数和治疗反应产生负面影响.

研究的目的:

研究慢性HF患者的铁状况和临床/心声学变量之间的关系.
评估铁缺乏对HF严重程度和左心室喷射率的影响.

主要方法:

对88名慢性HF患者进行了一项横截面描述性研究.
用全血细胞计,血清费里丁和转激素和度 (Tsat) 来评估铁状况.
评估了临床参数,包括HF严重程度 (NYHA类) 和LVEF.

主要成果:

使用Tsat.没有发现HF持续时间和铁状况之间的相关性.
在HF持续时间和血清费里水平之间存在弱负相关性.
与中度性HF (NYHA II) 相比,严重HF (NYHA III/IV级) 的患者中,缺铁的发生率明显高.
左心室喷射分数 (LVEF) 在缺铁和补铁组之间没有显著差异.
在ID严重程度和LVEF之间没有观察到显著的相关性.

结论:

缺铁可以加剧慢性心力衰竭的临床变化.
ID可能会降低标准HF治疗的有效性.
对于严重或不反应症状的HF患者,建议对铁缺乏症进行进一步评估.
实验室标记物如TSAT和血清费里丁有助于评估具有不良临床结果的患者.

关键词:

慢性心力衰竭是一种慢性心力衰竭.临床参数临床参数相关性相关性相关性一个横截面描述性研究.铁的状态铁的状态

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