在罗莎-多尔夫曼病中同步的中枢神经和中枢神经系统参与:一个病例报告
Carolina Soto-Davila1, Rachel Klapper1, Jacob Afude2
1Radiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Cureus
|July 7, 2023
概括
罗莎-多夫曼病 (RDD) 可以影响大脑,模仿脑膜瘤. 定子发射断层扫描/计算机断层扫描 (PET/CT) 有助于检测其他RDD部位,改善了这种罕见的囊细胞性疾病的诊断和管理.
科学领域:
- 神经学 神经学
- 病理学 病理学 病理学
- 放射学 放射学是一门学科.
背景情况:
- 罗莎伊-多夫曼病 (RDD) 是一种罕见的囊细胞性疾病.
- 它通常会影响淋巴结,但也可能发生在淋巴结外部,包括中枢神经系统.
- 中枢神经系统RDD可以呈现为大规模的病变,往往被误诊.
研究的目的:
- 要突出一个RDD呈现为大脑质量的案例.
- 强调在对脑损伤的差异诊断中考虑RDD的重要性.
- 评估PET/CT在识别 extranodal RDD活动中的实用性.
主要方法:
- 一个有神经症状的61岁妇女的病例报告.
- 磁共振成像 (MRI) 揭示了左侧外轴质量.
- 手术切除和组织病理学分析证实了RDD.
- 位子发射断层扫描/计算机断层扫描 (PET/CT) 用于分期.
主要成果:
- 组织病理学证实了具有特征性扩大的囊细胞的RDD (S100+,CD68+,CD163+,CD1a-).
- 最初的成像显示是脑膜瘤.
- 通过PET/CT检测发现了一种强烈的氧葡萄糖活跃的中枢淋巴结,这也与RDD一致.
结论:
- 在对脑病变的差异诊断中,特别是在模仿脑膜瘤的脑病变中,应该考虑RDD.
- PET/CT是检测外RDD活动的一个有价值的工具.
- 早期识别和全面的分期对于管理RDD至关重要.
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