风湿学中的非传染性尿道炎:模式,治疗和结果
Raheel Younus1, Muhammad A Saeed2, Muhammad Arshad1
1Rheumatology, National Hospital and Medical Centre, Lahore, PAK.
Cureus
|July 7, 2023
概括
前膜炎在巴基斯坦男性中最常见,通常与脊柱关节炎有关. 生物药物在非传染性紫外线炎治疗中显示出比常规疾病修饰性抗风湿药物更大的有效性.
科学领域:
- 类风湿病学 类风湿病学
- 眼科医生 眼科 眼科
- 免疫学 免疫学 免疫学
背景情况:
- 非传染性脑膜炎 (NIU) 是视力障碍的一个重要原因.
- 了解不同人群中NIU的具体模式和潜在原因对于有效管理至关重要.
- 风湿病学实践经常遇到NIU的患者,需要清楚地了解其呈现和关联.
研究的目的:
- 在巴基斯坦的风湿病学环境中确定非传染性脑膜炎的流行病学模式和病因学.
- 确定常见的治疗方法,并评估被诊断为NIU的患者的结果.
- 建立巴基斯坦人口中NIU的初步报告.
主要方法:
- 追溯横截面研究分析了2019年11月至2023年1月NIU诊断的52名患者的电子病历.
- 使用国际阴道管炎研究小组标准对阴道管炎模式 (前,中,后,阴道管炎) 和横向性进行分类.
- 通过尿道炎命名标准化 (SUN) 准则评估疾病活性,并分析治疗方式 (传统的DMARD与生物药物).
主要成果:
- 前膜炎是最常见的类型 (55.8%),主要影响男性 (59.6%).
- 脊椎关节炎 (SpA) 和异常原因是最常见的潜在疾病 (分别为34.6%和28.8%).
- 在治疗NIU时,生物DMARD与传统DMARD相比 (60%) 实现了更高的缓解率 (82%).
结论:
- 前膜炎是这个巴基斯坦队列中最常见的NIU形式,经常与脊髓关节炎相关,在男性中更为普遍.
- 人类白细胞抗原 (HLA) -B27特别与紫外线炎有关.
- 生物疗法在管理NIU方面表现出比cDMARDs更高的疗效,强调了跨学科合作对于改善患者治疗结果的重要性.
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