功能障碍的Pro1导致大米爆发真菌中的雌性不育
Momotaka Uchida1, Takahiro Konishi1, Ayaka Fujigasaki1
1Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan.
iScience
|July 7, 2023
概括
在大米爆发真菌中,女性生育能力的丧失与Pro1基因的突变有关. 这种遗传变化增加了状释放,可能有利于真菌.
科学领域:
- 菌类学 菌类学是指菌类学.
- 植物病理学 植物病理学
- 遗传学 是一个遗传学.
背景情况:
- 性繁殖在真核生物中很常见,但一些真菌,如Pyricularia (*Magnaporthe*) *oryzae*,可以无性繁殖.
- 虽然真菌起源的分离物是肥沃的,但大多数是雌性无菌的,这表明在传播期间的生育能力丧失.
研究的目的:
- 调查Pyricularia* (*Magnaporthe*) *oryzae* *女性生育能力丧失的遗传基础.
- 确定Pro1基因在女性不孕症中的作用及其对真菌生物学的影响.
主要方法:
- 通过在肥沃和无菌分离物之间进行逆交分析,确定了Pro1基因的突变.
- 评估了Pro1突变对感染过程和状释放的影响.
- 选了地理上多样化的P. oryzae*分离物,包括那些引起小麦爆发的P. oryzae*分离物,以检测Pro1突变.
主要成果:
- 功能突变在Pro1,一个关键的转录调节器,被确定为女性不育的原因.
- 功能障碍的Pro1并没有影响感染,但导致状释放增加.
- 在*P. oryzae*种群中发现了多种不同的Pro1突变,包括大流行小麦爆破分离物.
结论:
- *P. oryzae*的女性生育能力丧失与Pro1基因的突变有关.
- 改变的Pro1功能可能会给植物病原菌带来好处,例如增加状释放.
- 这项研究提供了第一个证据,证明女性不育在某些真菌病原体中可能具有进化上的优势.
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