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在前庭神经瘤的微手术后的复发和进展
Maximilian Scheer1, Sebastian Simmermacher1, Julian Prell1
1Department of Neurosurgery, Medical Faculty, University Hospital Halle, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.
Frontiers in surgery
|July 7, 2023
概括
瘤移除的程度显著影响前体神经瘤复发风险. 亚总切除带有最高风险,强调需要长期监测患者.
科学领域:
- 神经外科 神经外科
- 在瘤学瘤学.
- 听力学 听力学是指听力学.
背景情况:
- 静脉瘤 (VS) 治疗正在转向神经功能保护.
- 完整的VS去除已经显示了晚期复发,需要扩展后续协议.
研究的目的:
- 为了评估在接受微手术的患者中前庭瘤的复发和进展率.
- 为了确定前体 schwannoma 切除后复发的预测因素.
主要方法:
- 单边VS患者的回顾性分析,这些患者接受了初级的逆形微手术 (1995-2021).
- 瘤切除程度被分类为总切除 (GTR),近总切除 (NTR) 或亚总切除 (STR).
- 无放射性复发生存率是主要终点.
主要成果:
- 在386名患者中,28人经历了复发.
- 亚总切除 (STR) 显示,与GTR相比,复发风险高出近10倍.
- 接近全切除 (NTR) 显示复发风险几乎是GTR的3倍.
结论:
- 切除的程度是影响前庭神经瘤复发的关键因素.
- 长期跟踪,至少10年,至关重要,即使在粗整切除后.
- 大多数复发发生在手术后3-5年之间,但也观察到晚期复发.
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