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Updated: Jul 24, 2025

A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types
12:39

A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types

Published on: December 10, 2012

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GCPBayes管道:一种在基因层面探索性质的工具

Yazdan Asgari1, Pierre-Emmanuel Sugier1,2, Taban Baghfalaki3

  • 1Paris-Saclay University, UVSQ, Gustave Roussy, Inserm, CESP, Team Exposome and Heredity, 94807 Villejuif, France.

NAR genomics and bioinformatics
|July 7, 2023
PubMed
概括

这项研究引入了一个用户友好的管道,用于交叉表型基因组分析,有助于发现类基因和共享疾病机制. 该管道利用GCPBayes有效分析基因组规模数据并可视化结果,为复杂疾病提供新的见解.

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A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information

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A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes

Published on: May 22, 2018

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Genome-wide Association Studies-GWAS01:11

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Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
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When more than one gene is responsible for a given phenotype, the trait is considered polygenic. Human height is a polygenic trait. Studies have uncovered hundreds of loci that influence height, and there are believed to be many more. Due to the high number of genes involved, as well as environmental and nutritional factors, height varies significantly within a given population. The distribution of height forms a bell-shaped curve, with relatively few individuals in the population at the...
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