植物化学查,含量,和抗炎效果的虫的种子提取物
Asma Cherbal1,2, Mouna Bouabdallah1, Mouna Benhalla1
1Department of Molecular and Cell Biology, Faculty of Nature and Life Sciences, University of Jijel, Jijel 18000, Algeria.
Preventive nutrition and food science
|July 7, 2023
概括
的种子提取物通过抑制蛋白质变性和蛋白酶活性,显示出强大的抗炎性质. 这种天然化合物显示出作为潜在的抗炎剂的前景.
科学领域:
- 药理学 药理学是指药理学的学科.
- 自然产品化学 自然产品化学
背景情况:
- 药用植物是药物开发中生物活性化合物的重要来源.
- 传统医学经常利用植物,如Foeniculum vulgare用于治疗目的.
研究的目的:
- 为了研究从Foeniculum vulgare种子中提取的水甲醇提取物的化学成分.
- 为了评估这种提取物的体外抗炎潜力.
主要方法:
- 总,黄和黄含量的量定量.
- 气色谱-质谱 (GC-MS) 用于化学分析.
- 在体外测试蛋白质变性,蛋白酶活性,膜稳定和红细胞血液溶解.
主要成果:
- 提取物显著抑制了蛋白质变性 (35.68±0.4%) 和蛋白酶活性 (58.09±0.1%).
- 观察到红细胞中热诱导的血液溶解有显著的抑制 (9.67±0.3%).
- GC-MS确定了具有已知的抗炎功能的林纳醇和脂肪酸 (棕,油性脂肪酸).
结论:
- 菌种子的水甲醇提取物具有显著的体外抗炎活性.
- 黄类药物和已识别的化合物如林纳醇的存在可能有助于其治疗效果.
- 的种子提取物是未来抗炎药物开发的有希望的候选人.
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