在早产视网膜病变中不完全的外周视网膜血管化:这是改变氧和的结果吗?
Sigal Zmujack Yehiam1, Samantha K Simkin1, Rasha Al-Taie1,2
1Department of Ophthalmology, New Zealand National Eye Centre, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.
Frontiers in pediatrics
|July 7, 2023
概括
不完整的外周血管视网膜 (IPAR) 影响12.8%的早产婴儿进行过早性视网膜病变 (ROP) 查. 较高的氧和目标并没有增加IPAR患病率,这表明其他风险因素更为重要.
科学领域:
- 眼科医生 眼科 眼科
- 新生儿科学 新生儿科学
- 儿科医学 儿科医学
背景情况:
- 早产儿视网膜病变 (ROP) 查对早产儿至关重要.
- 不完整的外周血管视网膜 (IPAR) 是一个潜在的并发症.
- 了解IPAR的患病率和风险因素对于最佳的婴儿眼睛护理至关重要.
研究的目的:
- 确定针对ROP进行查的婴儿中IPAR的患病率和风险因素.
- 调查IPAR和氧和度 (SpO2) 目标之间的关联.
- 为了确定非血管视网膜发育的潜在风险因素.
主要方法:
- 对早产婴儿的视网膜图像进行了回顾性审查,这些婴儿被查ROP.
- 在增加SpO2目标之前和之后的IPAR患病率的比较.
- 排除同时患有眼部病理或ROP治疗的婴儿.
主要成果:
- 12.8%的婴儿 (62/486) 在最后的ROP查中表现出IPAR.
- 在2015年之前出生的婴儿 (第一组) 中,与之后 (第二组) 的婴儿 (p=0.043) 相比,观察到IPAR的患病率更高.
- 增加的SpO2目标与IPAR的更高患病率没有关联.
结论:
- 在ROP查的婴儿中,IPAR发生在12.8%的婴儿中.
- 更高的SpO2目标并没有提高IPAR流行率.
- 低妊娠年龄和低出生体重被怀疑是无血管视网膜的危险因素.
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