血液性恶性瘤中的COVID-19:病例系列和文献综述
Sunday Ocheni1, Theresa Ukamaka Nwagha1, Nneka Amu2
1Department of Haematology and Immunology, University of Nigeria; Department of Haematology and Immunology, University of Nigeria Teaching Hospital, Ituku-Ozalla Campus, Enugu, Nigeria.
患有血液性恶性瘤的患者面临更高的SARS-CoV-2感染严重结果的风险. 这份报告详细介绍了COVID-19大流行期间发生的两起致命病例,强调了这些癌症患者的脆弱性.
科学领域:
- 在瘤学瘤学.
- 传染性疾病 传染性疾病
- 血液学 血液学 血液学
背景情况:
- 癌症患者,特别是患有血液性恶性瘤的患者,患有严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 感染的风险增加.
- 早些时候的报道表明,癌症患者感染SARS-CoV-2的可能性翻了一番.
研究的目的:
- 在COVID-19大流行期间,在患有血液性恶性瘤的患者中描述了两例致命的SARS-CoV-2感染病例.
- 为了强调这种患者群体中严重疾病和死亡率的风险增加.
主要方法:
- 病例报告详细介绍了两名在COVID-19大流行期间接受治疗的患有血液性恶性瘤 (多发性骨髓瘤和霍奇金淋巴瘤) 的患者.
- 审查了临床数据,包括与SARS-CoV-2感染相关的诊断,治疗,症状和结果.
主要成果:
- 两名61岁和42岁的男性患者分别患有多发性骨髓瘤和霍奇金淋巴瘤,患有严重的SARS-CoV-2感染.
- 两位患者都经历了呼吸道损害 (低SPO2) 并最终死于感染,尽管医疗干预.
结论:
- 血液性恶性瘤及其治疗方法显著增加了SARS-CoV-2感染和严重疾病的风险.
- 与癌症和化疗相关的免疫抑制导致这些患者的预后不佳.
- 在病毒大流行期间,对于免疫力低下的癌症患者来说,紧急注意和保护措施至关重要.
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