相关实验视频
Updated: Jul 24, 2025

07:17
Studying Orthodontic Tooth Movement in Mice
Published on: August 2, 2024
782
卡尔西托宁作为一个药理学定在牙矯正中
Patrcia M Pizzo-Reis1, Monica C Coêlho2, Ricardo B Azevedo3
1Department of Orthodontics, School of Health Sciences, University of Brasília, Albany Medical Center, Brasília, DF, Brazil.
概括
鱼素通过局部作用促进了正牙固定,显著减少了老鼠的牙移动. 这种药理学剂没有影响血清水平,这表明在正牙治疗中具有局部效应.
科学领域:
- 生物医学科学 生物医学科学
- 矯正牙科 矯正牙科是一種矯正牙科.
- 药理学 药理学是指药理学的学科.
背景情况:
- ортодонтическая治疗涉及到控制的牙运动.
- 正在探索药理学药物来增强正义牙的定.
- 目前正在研究素在调节骨改造中对正的潜在作用.
研究的目的:
- 为了评估鱼酸作为一个药理学定剂在正牙科.
- 为了确定局部应用的酸对血清水平的影响.
- 用光显微镜观察牙和牙周组织对素的反应.
主要方法:
- 使用了Wistar大鼠,其中七只接受了当地的鱼素注射,七只作为对照.
- ортодонтические弹性带被用来诱导牙在牙之间移动.
- 14天后,分析了牙的移动,血清水平和组织组织变化.
主要成果:
- 与对照组 (0.236毫米) 相比,鱼酸组 (0.150毫米) 的牙运动明显减少.
- 在实验组和对照组之间没有发现血清水平的显著差异.
- 在光显微镜下进行的组织学分析为组织反应提供了洞察力.
结论:
- 鱼酸显示出促进正义牙固定的能力,可能是通过局部行动.
- 酸并没有完全抑制骨质细胞活动,但调节了对正义牙力量的反应.
- 局部托尼的使用似乎是一种可行的策略,可以增强正义牙的定,而不会对水平产生全身影响.
相关概念视频
Synthesis and Functions of Calcitonin
2.0K
Calcitonin, a vital polypeptide hormone, regulates calcium levels within body fluids. It is released by the parafollicular cells, also known as C cells, situated in the follicular epithelium of the thyroid gland. Calcitonin responds to fluctuations in blood calcium levels and the influence of gastrointestinal hormones like gastrin and cholecystokinin.
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
2.0K
Hormones and Bone Tissue
2.7K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
2.7K
Skeleton and Calcium Homeostasis
4.6K
Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
4.6K
The Parathyroid Glands
2.2K
The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
2.2K
Functions of Thyroid Hormones
2.8K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
2.8K
Teeth
507
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
507

