一项关于RLS在OSA的流行率和同时出现的后果的研究
Dipti Gothi1, Rahul Kumar1, Shweta Anand1
1Department of Pulmonary and Critical Care Medicine, ESI-PGIMSR, Basaidarapur, New Delhi, India.
Lung India : official organ of Indian Chest Society
|July 7, 2023
概括
不安腿综合征 (RLS) 在阻塞性睡眠呼吸暂停 (OSA) 患者中很常见. 科莫萨尔 (有RLS的OSA) 显示了更高的失眠率,精神病,代谢和认知障碍,以及慢性阻塞性呼吸道疾病 (COAD).
科学领域:
- 睡眠医学 睡眠医学
- 神经学 神经学
- 肺部病理学 肺部病理学
背景情况:
- 不安腿综合征 (RLS) 经常与阻塞性睡眠呼吸暂停 (OSA) 发生.
- 这种称为ComOSAR的并发症的临床意义尚未完全阐明.
- 了解COMOSAR对于全面的患者管理至关重要.
研究的目的:
- 为了确定与非OSA个体相比,在OSA患者中RLS的患病率.
- 调查ComOSAR与失眠,精神病,代谢,认知障碍和慢性阻塞性呼吸道疾病 (COAD) 的关联.
- 为了比较ComOSAR和单独的OSA中这些并发症的患病率.
主要方法:
- 一项前性观察性研究,涉及326名患者,被转诊进行多睡眠学 (PSG).
- 诊断OSA,RLS和失眠遵循了既定的指导方针.
- 患者被评估精神,代谢,认知障碍和COAD.
主要成果:
- 在OSA患者中RLS的患病率为24.4% (ComOSAR),类似于非OSA患者 (28.5%).
- 在COMOSAR患者中,失眠率 (26%对10.1%),精神疾病率 (73.7%对48.4%) 和认知缺陷率 (72.1%对54.7%) 显著增加.
- 伴随性代谢障碍 (57%vs34%) 和COAD (49%vs19%) 在ComOSAR中也明显更为普遍.
结论:
- 在OSA患者中对RLS进行查是必不可少的,因为相关并发症的患病率很高.
- 康莫沙尔与失眠,精神病,认知和代谢障碍的风险增加有关.
- 慢性阻塞性呼吸道疾病 (COAD) 在患有OSA和RLS并存的患者中也更常见.
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