与正常人相比,患有慢性病的埃及儿童的左心室质量和功能
Seham Mohammed Ramadan1, Abdelrahman M Hadeel1, Al Azizizi M Nashwa2
1Department of Pediatrics Faculty of Medicine, Zagazig University, Zagazig, Egypt.
概括
患有慢性病 (CKD) 接受血液透析 (HD) 的儿童显示左心室质量 (LVH) 增加和早期腹功能障碍. 建议定期进行心声回声扫描,以早期检测儿科CKD患者的心脏变化.
科学领域:
- 儿科脏病学 儿科脏病学
- 心脏病学 心脏病学
- 诊断成像 诊断成像 诊断成像
背景情况:
- 左心室缩 (LVH) 和心脏纤维化在慢性病 (CKD) 中很常见.
- 这些心脏变化可以使用心声回声学来评估.
- 功能障碍对儿科CKD患者心脏结构的影响需要进一步调查.
研究的目的:
- 调查功能障碍对左心室质量 (LVM) 和LVM指数 (LVMI) 对常规血液透析 (HD) 中的慢性病儿童的影响.
- 评估儿科慢性病患者的LVH和早期腹功能障碍.
- 探索心脏变化和生化因素 (如低热血症和维生素D缺乏) 之间的关系.
主要方法:
- 一项病例对照研究,涉及40名患有5期CKD的儿童在正常的HD和40名健康对照中.
- 使用二维心声学评估左心室质量 (LVM) 和LVM指数 (LVMI).
- 评估相对壁壁厚度和心肌流入速度 (E/A比率),以评估LVH和腹功能障碍.
主要成果:
- 与对照组相比,患有CKD或HD的儿童的LVMI (102.3 ± 19.1 g/m2 vs 49.6 ± 4.11 g/m2) 和相对壁厚都显著增加,这表明LVH是集中的.
- 慢性结核病患者表现出 mitra E 波速度和 E/A 速度比的显著下降,这表明早期的扩张功能障碍.
- 在CKD儿童中,LV质量变化与低血症和维生素D缺乏症密切相关.
结论:
- 患有CKD的儿童,特别是患有HD的儿童,容易发展左心室缩和早期腹功能障碍.
- 声心图评估对于早期检测儿科CKD心脏变化至关重要.
- 建议对患有CKD的儿童进行定期的心脏监测和及时干预,以管理相关的心血管风险.
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