[慢性囊炎:如何延长无复发期?]
E V Kulchavenya1,2,3,4,5, A I Neimark1,2,3,4,5, A Yu Tsukanov1,2,3,4,5
1FGBOU VO Novosibirsk State Medical University of Ministry of Health of Russia, Novosibirsk, Russia.
Urologiia (Moscow, Russia : 1999)
|July 7, 2023
概括
这项研究表明,在标准抗生素治疗中添加超级淋巴 suppositories 显著减少慢性囊炎 (尿路感染) 复发. 20天的10 IU Superlymph疗程在预防复发方面是最有效的.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- 慢性囊炎是尿路感染 (UTI) 的一种普遍形式.
- 目前的国际指导方针不充分解决慢性囊炎的管理问题.
- 需要针对慢性囊炎制定有效的治疗策略.
研究的目的:
- 评估Superlymph直肠假药的长期疗效与慢性囊炎的标准抗生素治疗相结合.
- 为了比较不同剂量和持续时间的超级淋巴治疗慢性囊炎管理.
主要方法:
- 一项前性多中心随机对照研究,涉及91名慢性囊炎患者.
- 建立了三组:单独使用标准抗生素治疗 (第一组),标准治疗加25IU超级淋巴液10天 (第二组),标准治疗加10IU超级淋巴液20天 (第三组).
- 标准治疗包括福米辛,甲醇和 furazidin. 患者在治疗后6个月的时间内进行了随访.
主要成果:
- 6个月后,10 IU超级淋巴组 (3 组) 的70.4%的患者仍然没有复发,而25 IU组 (2 组) 的44.4%,标准治疗组 (1 组) 的39.3%是这样.
- 在超级淋巴细胞组中,无复发期明显较长,在第三组中平均为123.5天.
- 两组之间复发率的差异在统计学上是显著的 (p<0.001).
结论:
- 结合病因和致病基因疗法,特别是使用10 IU超级淋巴管20天,显著减少慢性囊炎复发,并延长无复发期.
- 超淋巴直肠假药是慢性囊炎的有前途的辅助治疗方法.
- 在接受最佳Superlymph治疗方案的患者中,70.4%的患者长期无症状.
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