相关实验视频
Updated: Jul 24, 2025

06:08
A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
23.5K
叶绿细胞瘤最常见的是作为上腺附带瘤:一个大型三级中心的经验
Sunil Aggarwal1,2,3, Alessandro Prete1,2,3,4, Vasileios Chortis1,2,3
1Institute of Metabolism and Systems Research, University of Birmingham, Birmingham B15 2TT, UK.
The Journal of clinical endocrinology and metabolism
|July 7, 2023
概括
大多数染细胞瘤是偶然发现的上腺质量. 这些瘤通常在老年患者中检测到,具有独特的临床,生化和遗传特征,表明独特的瘤生物学.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 遗传学 是一个遗传学.
背景情况:
- 染细胞瘤 (上腺髓的罕见瘤) 越来越多地被诊断为上腺质量的偶然发现.
- 偶然检测到的染细胞瘤的具体特征和临床表现尚不清楚.
研究的目的:
- 为了确定偶然检测到的染细胞瘤的比例.
- 描述它们的临床,生物化学,放射学,遗传学和组织病理学特征.
- 分析随机检测到的染细胞瘤的后续数据.
主要方法:
- 在2010年1月至2022年10月期间在英国第三级护理中心对被诊断患有染细胞瘤的患者进行了回顾性审查.
- 诊断通过组织学证实或通过升高的甲基氨酸 (MN),成像检测结果,以及 metaiodobenzylguanidine 嗜好.
- 偶然发现的病例与由于症状或基因查发现的病例进行比较.
主要成果:
- 在167种叶染色细胞瘤中,69%是偶然检测到的,而28%是有症状的,15%是从遗传查中检测到的.
- 在老年患者 (中位数为62岁) 中发现了偶发性乳色细胞瘤,比症状性瘤更小 (中位数为42毫米).
- 遗传性倾向在偶然检测到的病例中 (15.3%) 与症状 (42.9%) 相比较低.
结论:
- 大多数染细胞瘤是偶然诊断的,并且具有不同的临床,放射学,生化和遗传特征.
- 在老年患者中检测,但在较小的尺寸上表明,对于偶然的色细胞瘤,潜在的不同基础瘤生物学.
相关概念视频
Adrenal Gland Disorders
1.6K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
1.6K
Anatomy of the Adrenal Glands
2.4K
The adrenal or supra-renal glands, situated above the kidneys and aligned with the twelfth rib, are paired pyramid-shaped structures crucial for the body's stress response. During stress, these glands secrete hormones vital for adaptive physiological reactions.
These glands possess a distinctive yellow tinge due to the stored cholesterol and fatty acids required for hormone synthesis. They are encased in a fibrous capsule and cushioned by fat.
The adrenal gland comprises two distinct...
These glands possess a distinctive yellow tinge due to the stored cholesterol and fatty acids required for hormone synthesis. They are encased in a fibrous capsule and cushioned by fat.
The adrenal gland comprises two distinct...
2.4K
Hormones of the Adrenal Glands
2.6K
Adrenal hormones play a pivotal role in maintaining the body's electrolyte balance and orchestrating responses to stress, showcasing the intricate functions of the adrenal cortex and medulla.
The adrenal cortex, a powerhouse of hormone synthesis, generates over two dozen corticosteroid hormones. The zona glomerulosa produces mineralocorticoids, exemplified by aldosterone, influencing the electrolyte composition of body fluids. The synthesis of glucocorticoids such as cortisol and...
The adrenal cortex, a powerhouse of hormone synthesis, generates over two dozen corticosteroid hormones. The zona glomerulosa produces mineralocorticoids, exemplified by aldosterone, influencing the electrolyte composition of body fluids. The synthesis of glucocorticoids such as cortisol and...
2.6K
Sympathetic Pathways: Collateral Ganglia and Adrenal Medulla
1.4K
The sympathetic pathways of the collateral ganglia and adrenal medulla serve unique but interconnected roles in the sympathetic response.
Collateral Ganglia
Sympathetic preganglionic axons reach the collateral ganglia along the route of splanchnic nerves. These nerves bypass the sympathetic trunk and communicate with sympathetic postganglionic neurons housed in the prevertebral ganglia. These ganglia supply the organs of the abdominopelvic cavity.
The greater splanchnic nerve, formed by the...
Collateral Ganglia
Sympathetic preganglionic axons reach the collateral ganglia along the route of splanchnic nerves. These nerves bypass the sympathetic trunk and communicate with sympathetic postganglionic neurons housed in the prevertebral ganglia. These ganglia supply the organs of the abdominopelvic cavity.
The greater splanchnic nerve, formed by the...
1.4K
Aneurysm II: Clinical Manifestations and Diagnostic Studies
10
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
10
Hypertension III: Clinical Manifestations and Diagnostic Studies
27
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
27

