大麻茶中的大麻素含量和它们转移到茶叶注水中的估计
Nadja Triesch1, Nansiya Vijayakumar1, Stefan Weigel1
1Department Safety in the Food Chain, German Federal Institute for Risk Assessment (BfR), Berlin, Germany.
概括
大麻茶含有大量的大麻素,主要是CBD和CBDA. 然而,用沸水造大麻茶会导致THC等大麻素在输液中的转移率非常低.
科学领域:
- 药理学 药理学是指药理学的学科.
- 食品科学 食品科学 食品科学
- 分析化学 分析化学
背景情况:
- 大麻茶是越来越受欢迎的饮料.
- 了解大麻素含量和提取方法对于产品质量和消费者安全至关重要.
- 大麻素具有各种潜在的治疗性质.
研究的目的:
- 为了确定各种大麻茶中的大麻素概况和含量.
- 量化单个大麻素从大麻茶转移到水性输液中的转移率.
- 评估造对大麻素生物可用性的影响.
主要方法:
- 使用标准化方法对23个麻茶样本进行大麻素含量的分析.
- 根据德国DIN标准协议制备茶叶注入剂.
- 在干茶材料和灌注中量化16种大麻素.
- 基于度差异计算大麻素转移速率.
主要成果:
- 干茶中的平均总大麻素含量为14,960毫克/公斤.
- 大麻二醇 (CBD) 和大麻二醇酸 (CBDA) 占大麻素总量的87%.
- 平均Δ9-四化甘醇 (Δ9-THC) 含量为221毫克/公斤.
- 由于水溶性有限,Δ9-THC的平均输入率仅为0.5%.
结论:
- 大麻茶是大麻素的丰富来源,特别是CBD/CBDA.
- 标准的热水输注对于从大麻茶中提取大麻素是低效的.
- 对大麻茶中大麻素的优化提取方法进行进一步的研究是有必要的.
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