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相关概念视频

Multiple Comparison Tests01:13

Multiple Comparison Tests

3.9K
Multiple comparison test, abbreviated as MCT, is a post hoc analysis generally performed after comparing multiple samples with one or more tests. An MCT will help identify a significantly different sample among multiple samples or a factor among multiple factors.
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...
3.9K

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相关实验视频

Updated: Jul 24, 2025

Untargeted Metabolomics from Biological Sources Using Ultraperformance Liquid Chromatography-High Resolution Mass Spectrometry UPLC-HRMS
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对于MRS研究的持续自动化分析工作流程

Helge Jörn Zöllner1,2, Christopher W Davies-Jenkins3,4, Erik G Lee5,6

  • 1Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, 600 N Wolfe St, Baltimore, MD, 21287, USA. hzoelln2@jhmi.edu.

Journal of medical systems
|July 7, 2023
PubMed
概括
此摘要是机器生成的。

我们开发了一个自动化工作流程用于磁共振光谱 (MRS) 数据分析,简化处理和质量控制. 这种自动化减少了手工工作,错误和成本,使MRS更容易获得大规模研究.

关键词:
这就是BIDS BIDS.线性组合建模的线性组合建模磁共振光谱学 磁共振光谱学这是NIFTI-MRS.这就是 Osprey 飞.可复制性 可复制性

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科学领域:

  • 神经科学是一个神经科学.
  • 医疗成像医学成像
  • 生物医学工程 生物医学工程

背景情况:

  • 磁共振光谱 (MRS) 在体内非侵入性地测量代谢物,对神经科学和临床研究至关重要.
  • 目前的MRS数据分析涉及广泛的手动步骤,阻碍了更广泛的采用,增加了错误,并限制了可扩展性.
  • 手动工作流程的变化为研究人员和临床医生创造了重大障碍.

研究的目的:

  • 为磁共振光谱 (MRS) 数据采集,处理和质量审查开发和演示完全自动化的端到端工作流.
  • 克服MRS中手动数据分析的局限性,包括时间消耗,人为错误的可能性和可扩展性问题.
  • 促进MRS在大规模研究和多中心合作中得到更广泛的应用.

主要方法:

  • 在新数据到达时,由目录监控服务触发的持续自动化分析工作流.
  • 数据存储公约的综合创新,包括转换到NIfTI-MRS格式和BIDS-MRS组织.
  • 利用开源软件Osprey进行命令行分析和自动化电子邮件交付质量控制报告.

主要成果:

  • 自动化架构成功地处理了一个示范数据集,使用最小的手动干预 (仅复制数据文件).
  • 工作流程有效地处理数据转换,组织,分析和质量评估.
  • 证明了从原始数据到质量控制结果的全自动化管道的可行性.

结论:

  • 持续自动化分析MRS数据,大大降低了手动处理和质量控制的负担.
  • 这种自动化对非专家用户,多中心研究和大规模研究计划特别有益.
  • 开发的工作流提供了实质性的经济优势,并促进了MRS的更广泛采用.