治疗儿科持续无症状的宫淋巴结核病
Jacqueline E Harris1, Neil N Patel1, Katherine Wai1
1Department of Otolaryngology-Head and Neck Surgery, University of California San Francisco Benioff Children's Hospital, San Francisco, California, USA.
概括
大多数儿科持续无症状的宫淋巴结核病 (PACL) 是良性的. 超声监测可以安全地管理PACL,避免不必要的切除活检和儿童的相关风险.
科学领域:
- 儿科耳鼻喉科 儿科耳鼻喉科
- 诊断成像 诊断成像 诊断成像
- 儿科手术 儿科手术
背景情况:
- 持续无症状的宫淋巴腺病变 (PACL) 是儿童耳鼻喉学转诊中经常出现的诊断.
- 在全身麻醉下切除活检是传统的诊断标准,但具有固有的风险.
- 对于儿童PACL的不那么侵入性监测策略存在有限的指导.
研究的目的:
- 评估儿科PACL超声波监测的安全性和有效性.
- 确定大多数患有PACL的儿童是否可以通过非侵入性方法避免切除活检.
主要方法:
- 18岁以下患有PACL的患者进行部超声波 (2007-2021) 的回顾性审查.
- 排除患有急性感染,先天性质量或已知的全身性疾病的患者.
- 多变量后勤回归用于识别影响外科手术决定的因素.
主要成果:
- 在197名患者中,有15.2%接受了手术活检;其中90%的患者发现了良性病理.
- 26%的患者进行了重复的超声波检查,显示了平均节点大小的减少.
- 超声波的疼痛,坚硬性和脂肪的缺失与手术管理相关.
结论:
- 大多数儿科PACL病例是良性的,不需要切除活检来排除淋巴瘤.
- 连续临床随访与部超声波相结合,为儿科PACL提供了一种安全的监测方法.
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