未诊断的阻塞性睡眠呼吸暂停和COVID-19的严重过程之间的关联:一个前性观察性研究
Natalia Celejewska-Wójcik1,2, Kamil Polok3,4, Karolina Górka3,5
1Department of Pulmonology and Allergology, University Hospital, Kraków, Poland. natalia.celejewska@uj.edu.pl.
Sleep & breathing = Schlaf & Atmung
|July 7, 2023
概括
以前未被诊断的阻塞性睡眠呼吸暂停 (OSA) 在住院的COVID-19患者中很普遍. 睡眠喘的严重程度与住院期间经历的呼吸衰竭程度相关.
科学领域:
- 肺部病理学 肺部病理学
- 睡眠医学 睡眠医学
- 传染性疾病 传染性疾病
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 与许多长期健康问题有关.
- 未诊断的OSA和COVID-19严重程度之间的关系需要进一步调查.
研究的目的:
- 在住院COVID-19患者中调查以前未被识别的阻塞性睡眠呼吸暂停 (OSA) 的患病率.
- 为了确定OSA是否与COVID-19患者呼吸衰竭严重程度的增加有关.
主要方法:
- 在波兰,125名住院的COVID-19患者完成了OSA查问卷 (ESS,STOP-BANG,BQ,OSA-50,没有SAS).
- 测谎仪在24小时后进行,无需补充氧气.
- 多变量分析评估了OSA严重程度指标与呼吸支持需求之间的关联.
主要成果:
- 82%的患者 (103/125) 被诊断出患有OSA,其中33%是轻度,24%是中度,26%是严重.
- 68% (85/125) 的患者需要高级呼吸辅助;7% (8/125) 需要输管.
- 增加呼吸支需求与更高的呼吸事件指数,氧气脱度指数和低氧负担以及较低的最小 SpO2.2 相关.
结论:
- 未被诊断的OSA在幸存于急性阶段的COVID-19患者中很常见.
- 阻塞性睡眠呼吸暂停的严重程度与住院COVID-19患者呼吸衰竭的严重程度直接相关.
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