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Equipments Used To Measure Blood Pressure01:30

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This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...
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相关实验视频

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In Vitro Thrombosis Test for Ventricular Assist Devices
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音乐盒灵感的半自动血红素验证设备

You-Mao Liao1, Ping-Yeh Chiu2, Yuh-Shiuan Chien1

  • 1Institute of Applied Mechanics, National Taiwan University, Taipei 106, Taiwan.

ACS sensors
|July 7, 2023
PubMed
概括

这项研究介绍了tFuge,一个便携式,无电的离心机,用于测量血红素 (HCT). 该设备提供精确的心血管疾病风险评估,使用最少的血液,即使在资源有限的环境中.

关键词:
抵制效应的抵制效应恒定扭矩机制的机制.血红素的血红素位数是什么医疗服务点检测试验便携式离心机是一种便携式离心机.

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科学领域:

  • 生物医学工程 生物医学工程
  • 临床诊断 临床诊断 临床诊断 临床诊断
  • 心血管疾病风险评估心血管疾病风险评估

背景情况:

  • 高血红素水平 (HCT) 与心血管疾病风险有关.
  • 目前的HCT测量方法 (离心) 通常是重的,昂贵的,并且需要电力.
  • 可访问的HCT监测对于早期心血管疾病诊断至关重要.

研究的目的:

  • 开发一个半自动,便携式,不需要电的设备,用于HCT测量.
  • 创建一个具有成本效益和用户友好的替代传统离心机.
  • 为了在护理地点进行快速的HCT评估.

主要方法:

  • 开发的tFuge,一个扭矩驱动,音乐盒灵感的半自动离心机.
  • 利用抵制效应进行高效的血细胞沉.
  • 采用恒定扭矩机制,以保持一致的运行.
  • 在旋转盘上打印校准的梯度数,以便直接读取HCT.

主要成果:

  • 在tFuge实现了可重复的HCT测量在不同的用户.
  • 在10-60%的HCT范围内,HCT水平和血细胞沉积长度 (R2 = 0.99) 之间显示出高线性.
  • 在不到4分钟的时间内完成了测试,仅使用10μL的血从指尖刺伤.

结论:

  • tFuge是一个可行的,便携式,不需要电的HCT测量设备.
  • 它为传统的微血离心机提供了潜在的替代品,特别是在资源有限的地区.
  • 通过在护理地点进行HCT测试,促进了可访问的心血管疾病风险查.