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Updated: Jul 24, 2025

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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病原体和人类NDPK蛋白通过单细胞NLRP3-炎症酶激活促进AML细胞存活

Sandro Trova1, Fei Lin1, Santosh Lomada2

  • 1School of Biosciences, University of Birmingham, Birmingham, United Kingdom.

PloS one
|July 7, 2023
PubMed
概括

病原体衍生的核酸二酸激酶 (NDPK) 模仿人类的NM23-H1,促进急性髓性白血病 (AML) 细胞存活. 这些细菌NDPK通过NLRP3炎症体激活单细胞,涉及AML和骨髓质综合征 (MDS) 发病的感染.

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