纯尿酸石头预测模型使用值3D细分方法测量石头密度的变异系数:一个多中心研究
Bong-Il Song1, Jinny Lee1, Wonho Jung2
1Department of Nuclear Medicine, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, 130 Dongdeok-ro, Jung-gu, Daegu 41944, Korea (the Republic of).
Computer methods and programs in biomedicine
|July 7, 2023
概括
使用变异石密度系数 (VCSD) 的新方法可以从CT扫描中识别纯尿酸 (UA) 石头. 这种非侵入性预测模型有助于临床决策,可能减少尿路结石的手术治疗.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 放射学 放射学是一门学科.
- 医学成像分析 医学成像分析
背景情况:
- 尿路结石在全球普遍存在,尿酸结石可以通过口服化解来治疗.
- 目前的管理往往涉及侵入性手术,突出了非手术替代品的需要.
研究的目的:
- 开发和验证纯尿酸 (pUA) 结石的预测模型.
- 利用从非对比CT图像中获得的岩石密度变量系数 (VCSD).
主要方法:
- 使用基于3D细分的方法,使用130 HU值来分析CT图像.
- VCSD被计算为石材异质性指数除以平均石材密度.
- 该研究包括培训,内部验证和外部验证数据集.
主要成果:
- 预测模型确定VCSD是pUA石头最强大的独立预测器.
- 该模型表现出高差异性,在各自的验证集中AUC为0.960,0.931和0.938.
- 关键预测因素包括VCSD,年龄,性别,放射性不透明度,高血压,糖尿病和尿液pH.
结论:
- 来自3D细分的VCSD是识别纯尿酸结石的重要预测因素.
- 开发的预测模型为pUA石头识别提供了一个非侵入性的术前工具,可能指导治疗决策.
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