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Updated: Jul 24, 2025

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对N-alkyl-N'-aryl尿素进行符合性研究,以告知药物发现

Hannah L Stewart1, Marta Bon2, Corinne Wills3

  • 1Cancer Research Horizons Therapeutic Innovation Newcastle Drug Discovery Group, Chemistry, School of Natural and Environmental Sciences, Bedson Building, Newcastle University, NE1 7RU, UK.

Bioorganic & medicinal chemistry
|July 7, 2023
PubMed
概括

甲基化模式显著影响尿素构成. N-phenyl-N'-cyclopentyl尿素采用了trans-trans和cis-trans两种形式,其中cis-trans通过键稳定,有助于药物设计.

关键词:
密度函数理论密度函数理论药物发现 药物发现尿素形状的尿素.

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